S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate

Modify Date: 2024-01-14 06:00:33

S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate structure	Common Name	S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate
	CAS Number	2905-15-9	Molecular Weight	286.31800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₈F₂O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate

Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].

Name	S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate
Synonym	More Synonyms

Description	Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	IC50: 1.2 µM (tubulin)[1].
References	[1]. Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.

Molecular Formula	C₁₂H₈F₂O₂S₂
Molecular Weight	286.31800
Exact Mass	285.99300
PSA	67.82000
LogP	4.52660

S-p-fluorophenyl p-fluorobenzenethiosulfonate

p,p'-Di-fluor-phenylsulfonylthiophenol

p-Fluorphenyl-p-fluorbenzolthiosulfonat

S-4-fluorophenyl 4-fluorobenzenesulfonothioate

S-4-fluorophenyl 4-fluorobenzenethiosulfonate

S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate

Use of S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate

Names

Biological Activity

Chemical & Physical Properties

Synonyms