2′-Deoxy-8-(methylthio)adenosine

Modify Date: 2024-01-07 19:05:25

2′-Deoxy-8-(methylthio)adenosine Structure
2′-Deoxy-8-(methylthio)adenosine structure
Common Name 2′-Deoxy-8-(methylthio)adenosine
CAS Number 29836-02-0 Molecular Weight 295.36
Density N/A Boiling Point N/A
Molecular Formula C12H17N5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2′-Deoxy-8-(methylthio)adenosine


2′-Deoxy-8-(methylthio)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 8-(methylthio)-2'-deoxyadenosine
Synonym More Synonyms

 2′-Deoxy-8-(methylthio)adenosine Biological Activity

Description 2′-Deoxy-8-(methylthio)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C12H17N5O2S
Molecular Weight 295.36
Exact Mass 297.09000
PSA 144.61000
LogP 0.35230

 Synonyms

8-methylsulfanyl-2'-deoxy-adenosine
8-methylthio-2'-deoxyadenosine