(Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt

Modify Date: 2024-01-03 10:50:45

(Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt structure	Common Name	(Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt
	CAS Number	299898-52-5	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂₆H₃₃₈N₆₀O₆₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt

(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) is an efficacious, stable and specific human GIP receptor (hGIPR) full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with Ki/ Kd values of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes[1][2].

Name	(Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt

Description	(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) is an efficacious, stable and specific human GIP receptor (hGIPR) full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with Ki/ Kd values of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes[1][2].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor
Target	EC50: 0.026 nM (hGIPR)[2] Ki/Kd: 0.90 nM (hGIPR); 1.1 nM (Rat GIPR); 0.72 nM (Mouse GIPR)[2]
In Vitro	(Pro3) GIP, human induces cAMP accumulation with an EC50 value of 0.026 nM[2]. (Pro3) GIP, human has high binding affinity for human GIPR, Rat GIPR and Mouse GIPR with Ki/ Kd values of 0.90 nM, 1.1 nM and 0.72 nM, respectively[2].
In Vivo	(Pro3) GIP, human has comparatively weak partial agonist effect in rodent models[2].

Molecular Formula	C₂₂₆H₃₃₈N₆₀O₆₄S

(Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt

Use of (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt

Names

Biological Activity

Chemical & Physical Properties