Boc-N-PEG2-Ms

Modify Date: 2024-01-04 10:32:43

Boc-N-PEG2-Ms Structure
Boc-N-PEG2-Ms structure
Common Name Boc-N-PEG2-Ms
CAS Number 302331-20-0 Molecular Weight 283.34200
Density N/A Boiling Point N/A
Molecular Formula C10H21NO6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-N-PEG2-Ms


Boc-N-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-tert-butoxycarbonylaminoethoxy)ethanol methanesulfonic ester
Synonym More Synonyms

 Boc-N-PEG2-Ms Biological Activity

Description Boc-N-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H21NO6S
Molecular Weight 283.34200
Exact Mass 283.10900
PSA 99.31000
LogP 1.97560

 Synonyms

2-[2-(tert-Butoxycarbonylamino)ethoxy]ethyl methanesulfonate
1-(2-(tert-butyloxycarbonylamino)ethoxy)-2-sulfonylethane
2-(2-(tert-butoxycarbonylamino)ethoxy)ethyl methanesulfonate
2-[2-(tert-butoxycarbonylamino)ethoxy]ethyl methanesulfonate
2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate
2-{2-[(tert-butoxycarbonyl)amino]ethoxy}ethyl methanesulfonate