5-Methoxy-2-thiouridine

Modify Date: 2024-02-17 20:07:40

5-Methoxy-2-thiouridine Structure
5-Methoxy-2-thiouridine structure
Common Name 5-Methoxy-2-thiouridine
CAS Number 30771-43-8 Molecular Weight 290.29
Density N/A Boiling Point N/A
Molecular Formula C10H14N2O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methoxy-2-thiouridine


5-Methoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-2-sulfanylidenepyrimidin-4-one
Synonym More Synonyms

 5-Methoxy-2-thiouridine Biological Activity

Description 5-Methoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C10H14N2O6S
Molecular Weight 290.29
Exact Mass 290.05700
PSA 149.29000

 Synonyms

Uridine,5-methoxy-2-thio