Bikaverin

Modify Date: 2024-01-14 17:05:44

Bikaverin Structure
Bikaverin structure
Common Name Bikaverin
CAS Number 33390-21-5 Molecular Weight 382.32000
Density 1.61g/cm3 Boiling Point 719.8ºC at 760mmHg
Molecular Formula C20H14O8 Melting Point N/A
MSDS Chinese USA Flash Point 263.3ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of Bikaverin


Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi[1].

 Names

Name bikaverin
Synonym More Synonyms

 Bikaverin Biological Activity

Description Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi[1].
Related Catalog
In Vitro Chemically, Bikaverin (Lycopersin) is a polyketide with a tetracyclic benzoxanthone structure, resulting from the activity of a specific class I multifunctional polyketide synthase and subsequent group modifications introduced by a monooxygenase and an O-methyltransferase[1]. Bikaverin is a reddish polyketide pigment produced by Gibberella fujikuroi in addition to large amounts of gibberellins[2].
References

[1]. Limón MC, et al. Bikaverin production and applications. Appl Microbiol Biotechnol. 2010;87(1):21-29.

[2]. Lale GJ, Gadre RV. Production of bikaverin by a Fusarium fujikuroi mutant in submerged cultures. AMB Express. 2016;6(1):34.

 Chemical & Physical Properties

Density 1.61g/cm3
Boiling Point 719.8ºC at 760mmHg
Molecular Formula C20H14O8
Molecular Weight 382.32000
Flash Point 263.3ºC
Exact Mass 382.06900
PSA 123.27000
LogP 2.58370
Index of Refraction 1.711

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM2901000
CHEMICAL NAME :
10H-Benzo(b)xanthene-7,10,12-trione, 6,11-dihydroxy-3,8-dimethoxy-1-methyl-
CAS REGISTRY NUMBER :
33390-21-5
BEILSTEIN REFERENCE NO. :
0358013
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H14-O8
MOLECULAR WEIGHT :
382.34
WISWESSER LINE NOTATION :
T E6 C666 BO FV IV MVJ DQ GO1 KQ O1 QO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Cells - not otherwise specified
DOSE/DURATION :
4200 ug/L
REFERENCE :
NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 22,335,1975

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII
RTECS DM2901000

 Synthetic Route

 Articles25

More Articles
Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans.

J. Appl. Microbiol. 104(3) , 692-8, (2008)

To isolate and identify antioomycete substances from Fusarium oxysporum EF119 against Phytophthora infestans and to investigate their antimicrobial activities against various plant pathogenic bacteria...

United States Department of Agriculture-Agricultural Research Service studies on polyketide toxins of Fusarium oxysporum f sp vasinfectum: potential targets for disease control.

Pest Manag. Sci. 59(6-7) , 736-47, (2003)

A group of 133 isolates of the cotton wilt pathogen Fusarium oxysporum Schlecht f sp vasinfectum (Atk) Sny & Hans, representing five races and 20 vegetative compatibility groups within race 1 were use...

GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.

Mycologia 100(5) , 701-9, (2008)

Fusarium verticillioides (teleomorph Gibberella moniliformis) is an ascomycete known to produce a variety of secondary metabolites, including fumonisins, fusaric acid and bikaverin. These metabolites ...

 Synonyms

Lycopersin
Bikaverin
6,11-dihydroxy-3,8-dimethoxy-1-methylbenzo[b]xanthene-7,10,12-trione
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