Gartanin

Modify Date: 2024-01-03 17:48:43

Gartanin Structure
Gartanin structure
 Common Name Gartanin
CAS Number 33390-42-0 Molecular Weight 396.433
Density 1.3±0.1 g/cm3 Boiling Point 644.4±55.0 °C at 760 mmHg
Molecular Formula C23H24O6 Melting Point N/A
MSDS N/A Flash Point 224.9±25.0 °C

 Use of Gartanin


Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells[1][2].

 Names

Name gartanin
Synonym More Synonyms

 Gartanin Biological Activity

Description Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells[1][2].
Related Catalog
In Vitro Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways [1]. Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells [1].
References

[1]. Gao XY, et al. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK. Neurochem Res. 2016 Sep;41(9):2267-77.

[2]. Kim MO, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34(1):139-46.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 644.4±55.0 °C at 760 mmHg
Molecular Formula C23H24O6
Molecular Weight 396.433
Flash Point 224.9±25.0 °C
Exact Mass 396.157288
PSA 111.13000
LogP 4.51
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.656

 Safety Information

Hazard Codes Xi
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
Gartanin
9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-
1,3,5,8-tetrahydroxy-2,4-bis(3-methylbut-2-enyl)xanthen-9-one
Gartinin
1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)-
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