Safrazine
Modify Date: 2024-01-09 16:58:30
Safrazine structure
|
Common Name | Safrazine | ||
|---|---|---|---|---|
| CAS Number | 33419-68-0 | Molecular Weight | 208.25700 | |
| Density | 1.161g/cm3 | Boiling Point | 368.9ºC at 760 mmHg | |
| Molecular Formula | C11H16N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 176.9ºC | |
Use of SafrazineSafrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1]. |
| Name | [4-(1,3-Benzodioxol-5-yl)-2-butanyl]hydrazine |
|---|---|
| Synonym | More Synonyms |
| Description | Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Safrazine (0.1-0.5 μM; 0-80 min) strengthenes the inhibitory potency by preincubation in a time-dependent manner[1]. |
| In Vivo | Safrazine (oral; 3, 10, 30 mg/kg) causes the increases contents of monoamine lasted for at least 24 h[1]. Safrazine strongly inhibits both 5-HT and PEA deaminations, but shows no selectivity toward the substrate used[1]. Animal Model: Male ddY mice[1] Dosage: 3, 10, 30 mg/kg Administration: Oral Result: Inhibited significantly both 5-HT and PEA deaminations at only 3 mg/kg by 77% and 71%, respectively. Completely reduced both deaminations at 10 and 30 mg/kg and not observed specificity toward substrates. |
| Density | 1.161g/cm3 |
|---|---|
| Boiling Point | 368.9ºC at 760 mmHg |
| Molecular Formula | C11H16N2O2 |
| Molecular Weight | 208.25700 |
| Flash Point | 176.9ºC |
| Exact Mass | 208.12100 |
| PSA | 56.51000 |
| LogP | 2.29090 |
| Vapour Pressure | 1.24E-05mmHg at 25°C |
| Index of Refraction | 1.563 |
| HS Code | 2934999090 |
|---|
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| [3-(1,2,3-triphenylcyclopropenyl)]-9'-cyanofluorene |
| 9H-Fluorene-9-carbonitrile,9-(1,2,3-triphenyl-2-cyclopropen-1-yl) |
| [3-(1,3-benzodioxol-5-yl)-1-methyl-propyl]hydrazine |
| 1-methyl-3-(3,4-methylenedioxyphenyl)propylhydrazine |
| 1-Piperonyl-2-hydrazinopropan |