Name | [4-(1,3-Benzodioxol-5-yl)-2-butanyl]hydrazine |
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Synonyms |
[3-(1,2,3-triphenylcyclopropenyl)]-9'-cyanofluorene
9H-Fluorene-9-carbonitrile,9-(1,2,3-triphenyl-2-cyclopropen-1-yl) [3-(1,3-benzodioxol-5-yl)-1-methyl-propyl]hydrazine 1-methyl-3-(3,4-methylenedioxyphenyl)propylhydrazine 1-Piperonyl-2-hydrazinopropan |
Description | Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1]. |
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Related Catalog | |
In Vitro | Safrazine (0.1-0.5 μM; 0-80 min) strengthenes the inhibitory potency by preincubation in a time-dependent manner[1]. |
In Vivo | Safrazine (oral; 3, 10, 30 mg/kg) causes the increases contents of monoamine lasted for at least 24 h[1]. Safrazine strongly inhibits both 5-HT and PEA deaminations, but shows no selectivity toward the substrate used[1]. Animal Model: Male ddY mice[1] Dosage: 3, 10, 30 mg/kg Administration: Oral Result: Inhibited significantly both 5-HT and PEA deaminations at only 3 mg/kg by 77% and 71%, respectively. Completely reduced both deaminations at 10 and 30 mg/kg and not observed specificity toward substrates. |
Density | 1.161g/cm3 |
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Boiling Point | 368.9ºC at 760 mmHg |
Molecular Formula | C11H16N2O2 |
Molecular Weight | 208.25700 |
Flash Point | 176.9ºC |
Exact Mass | 208.12100 |
PSA | 56.51000 |
LogP | 2.29090 |
Vapour Pressure | 1.24E-05mmHg at 25°C |
Index of Refraction | 1.563 |
HS Code | 2934999090 |
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HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |