2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo-

Modify Date: 2024-02-04 19:57:00

2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo- Structure
2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo- structure
Common Name 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo-
CAS Number 3370-69-2 Molecular Weight 323.10
Density 2.043g/cm3 Boiling Point N/A
Molecular Formula C9H11BrN2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo-


1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

Description 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.043g/cm3
Molecular Formula C9H11BrN2O6
Molecular Weight 323.10
Exact Mass 321.98000
PSA 124.78000

 Synonyms

5-BroMoarabinouridine