5-Bromo-2’-O-methyluridine

Modify Date: 2024-01-07 11:15:51

5-Bromo-2’-O-methyluridine Structure
5-Bromo-2’-O-methyluridine structure
Common Name 5-Bromo-2’-O-methyluridine
CAS Number 34218-83-2 Molecular Weight 335.15
Density N/A Boiling Point N/A
Molecular Formula C11H15BrN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Bromo-2’-O-methyluridine


5-Bromo-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-bromo-2'-O-methyluridine
Synonym More Synonyms

 5-Bromo-2’-O-methyluridine Biological Activity

Description 5-Bromo-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H15BrN2O5
Molecular Weight 335.15
Exact Mass 335.99600
PSA 113.78000

 Synonyms

5-Bromo-2'-O-methyluridin
5-Bromo-1-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione