D-Tetrahydropalmatine

Modify Date: 2024-01-02 12:11:31

D-Tetrahydropalmatine structure	Common Name	D-Tetrahydropalmatine
	CAS Number	3520-14-7	Molecular Weight	355.427
	Density	1.2±0.1 g/cm3	Boiling Point	482.9±45.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₅NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	138.7±25.9 °C

Use of D-Tetrahydropalmatine

D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis[1]. D-Tetrahydropalmatine is a Dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors[2]. D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor[3].

Name	D-Tetrahydropalmatine
Synonym	More Synonyms

Description	D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis[1]. D-Tetrahydropalmatine is a Dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors[2]. D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor[3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Metabolic Disease
Target	DA[2], OCT1[3]
References	[1]. Ma ZJ, et al. [Effects of different types and standard of processing vinegaron inherent constituents in rhizoma of Corydalis yanhusuo]. Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):465-7. [2]. Xu SX, et al. Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo Yao Li Xue Bao. 1989 Mar;10(2):104-10. [3]. Tu M, et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important rolein its hepatotoxicity. Toxicology. 2013 Sep 15;311(3):225-30.

Density	1.2±0.1 g/cm3
Boiling Point	482.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₅NO₄
Molecular Weight	355.427
Flash Point	138.7±25.9 °C
Exact Mass	355.178345
PSA	40.16000
LogP	3.70
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.609