N-ACETYLNEURAMIN-LACTOSE

Modify Date: 2024-01-02 17:34:40

N-ACETYLNEURAMIN-LACTOSE structure	Common Name	N-ACETYLNEURAMIN-LACTOSE
	CAS Number	35890-39-2	Molecular Weight	633.55
	Density	1.72 g/cm3	Boiling Point	1134.9ºC at 760 mmHg
	Molecular Formula	C₂₃H₃₉NO₁₉	Melting Point	N/A
	MSDS	N/A	Flash Point	640.1ºC

Use of N-ACETYLNEURAMIN-LACTOSE

6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis[1][2].

Name	(2R,4S,5R,6R)-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-2-[[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxyoxan-2-yl]methoxy]oxane-2-carboxylic acid
Synonym	More Synonyms

Description	6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
In Vitro	6'-Sialyllactose (10 mg/mL; 补充婴儿配方奶粉) 以剂量依赖性方式预防小鼠坏死性小肠结肠炎 (NEC)[1]。
References	[1]. Sodhi CP, et, al. The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling. Pediatr Res. 2021 Jan;89(1):91-101. [2]. Zhu Y, et, al. Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3'-sialyllactose and 6'-sialyllactose. Biotechnol Adv. 2023 Jan-Feb;62:108058.

Density	1.72 g/cm3
Boiling Point	1134.9ºC at 760 mmHg
Molecular Formula	C₂₃H₃₉NO₁₉
Molecular Weight	633.55
Flash Point	640.1ºC
Exact Mass	633.21200
PSA	342.92000