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35890-39-2

35890-39-2 structure
35890-39-2 structure
  • Name: N-ACETYLNEURAMIN-LACTOSE
  • Chemical Name: (2R,4S,5R,6R)-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-2-[[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxyoxan-2-yl]methoxy]oxane-2-carboxylic acid
  • CAS Number: 35890-39-2
  • Molecular Formula: C23H39NO19
  • Molecular Weight: 633.55
  • Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
  • Create Date: 2017-02-21 18:48:46
  • Modify Date: 2024-01-02 17:34:40
  • 6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis[1][2].

Name (2R,4S,5R,6R)-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-2-[[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxyoxan-2-yl]methoxy]oxane-2-carboxylic acid
Synonyms 6'-Sialyllactose (6'-SL)
6'-Sialyllactose
6'-Monosialyllactose
6’-Sialyllactose
6'-a-Sialyllactose
Description 6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis[1][2].
Related Catalog
In Vitro 6'-Sialyllactose (10 mg/mL; 补充婴儿配方奶粉) 以剂量依赖性方式预防小鼠坏死性小肠结肠炎 (NEC)[1]。
References

[1]. Sodhi CP, et, al. The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling. Pediatr Res. 2021 Jan;89(1):91-101.  

[2]. Zhu Y, et, al. Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3'-sialyllactose and 6'-sialyllactose. Biotechnol Adv. 2023 Jan-Feb;62:108058.  

Density 1.72 g/cm3
Boiling Point 1134.9ºC at 760 mmHg
Molecular Formula C23H39NO19
Molecular Weight 633.55
Flash Point 640.1ºC
Exact Mass 633.21200
PSA 342.92000
Hazard Codes Xi
WGK Germany 3