CAY10499

Modify Date: 2024-01-03 14:13:39

CAY10499 structure	Common Name	CAY10499
	CAS Number	359714-55-9	Molecular Weight	355.345
	Density	1.3±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CAY10499

MAGL-IN-5 is a non-selective lipase inhibitor with IC50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL),hormone sensitive lipase(HSL), and fatty acid amide hydrolase(FAAH) respectively[1][2].

Name	cay10499
Synonym	More Synonyms

Description	MAGL-IN-5 is a non-selective lipase inhibitor with IC50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL),hormone sensitive lipase(HSL), and fatty acid amide hydrolase(FAAH) respectively[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Metabolic Disease Signaling Pathways >> Neuronal Signaling >> FAAH
References	[1]. Muccioli GG, et al. CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. Chembiochem. 2008 Nov 3;9(16):2704-10. [2]. Granchi C, et al. 4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31(1):137-46.

Description

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL

Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH

Research Areas >> Metabolic Disease

Signaling Pathways >> Neuronal Signaling >> FAAH

References

[1]. Muccioli GG, et al. CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. Chembiochem. 2008 Nov 3;9(16):2704-10.

[2]. Granchi C, et al. 4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31(1):137-46.