Fibrinopeptide B (human) acetate salt

Modify Date: 2024-01-01 22:22:24

Fibrinopeptide B (human) acetate salt structure	Common Name	Fibrinopeptide B (human) acetate salt
	CAS Number	36204-23-6	Molecular Weight	1552.56000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₆H₉₃N₁₉O₂₅	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Fibrinopeptide B (human) acetate salt

Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

Name	Fibrinopeptide B
Synonym	More Synonyms

Description	Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
Related Catalog	Signaling Pathways >> Others >> Others Peptides Research Areas >> Inflammation/Immunology
In Vitro	Fibrinopeptide B, human is released from the amino-terminus of the B 3-chains of fibrinogen by thrombin. Fibrinopeptide B, human (hFpB, 10 nM) causes directed cell migration of neutrophils (PMN), and fibroblasts. Fibrinopeptide B, human also possesses potent chemotactic activity relative to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP), and for fibroblasts its chemotactic activity is comparable to that of platelet-derived growth factor. However, Fibrinopeptide B, human is not chemotactic for monocytes, and shows no interaction with PMN receptor for C5a, LTB4, or fMLP[1].
References	[1]. Senior RM, et al. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest. 1986 Mar;77(3):1014-9.

Molecular Formula	C₆₆H₉₃N₁₉O₂₅
Molecular Weight	1552.56000
Exact Mass	1551.66000
PSA	724.91000
Storage condition	−20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

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Fibrinopeptide B, human