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119418-04-1

119418-04-1 structure
119418-04-1 structure
  • Name: Galanin (human) acetate salt
  • Chemical Name: Galanin human
  • CAS Number: 119418-04-1
  • Molecular Formula: C139H210N42O43
  • Molecular Weight: 3157.41000
  • Catalog: Peptides
  • Create Date: 2018-07-14 10:39:07
  • Modify Date: 2024-01-02 17:11:32
  • Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.

Name Galanin human
Synonyms MFCD00135986
Galanin,Human
Galanin-1-30
Galanin (1-30), human
Description Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.
Related Catalog
Target

Kd: 1 nM (GalR1 receptor), 1 nM (GalR2 receptor)[2]

In Vitro Galanin (1-30), human (Gal1-30) is an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM[1]. Galanin (1-30), human displaces 125I-labeled rat galanin with a Kd of 0.5 nM. Galanin (1-30), human (hGal) causes contractions of isolated longitudinal rat fundus strips, with an ED50 of 13.8 ± 1.6 nM[2].
References

[1]. Hua XY, et al. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb;308(2):574-82.

[2]. Schmidt WE, et al. Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11435-9.

Molecular Formula C139H210N42O43
Molecular Weight 3157.41000
Exact Mass 3155.55000
PSA 1367.68000
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3