Neosolaniol

Modify Date: 2024-01-08 18:26:15

Neosolaniol Structure
Neosolaniol structure
Common Name Neosolaniol
CAS Number 36519-25-2 Molecular Weight 382.405
Density 1.4±0.1 g/cm3 Boiling Point 515.9±50.0 °C at 760 mmHg
Molecular Formula C19H26O8 Melting Point 171.5°C
MSDS Chinese USA Flash Point 180.2±23.6 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of Neosolaniol


Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].

 Names

Name Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 515.9±50.0 °C at 760 mmHg
Melting Point 171.5°C
Molecular Formula C19H26O8
Molecular Weight 382.405
Flash Point 180.2±23.6 °C
Exact Mass 382.162781
PSA 114.82000
LogP -0.07
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.578
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YD0080000
CHEMICAL NAME :
Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate
CAS REGISTRY NUMBER :
36519-25-2
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H26-O8
MOLECULAR WEIGHT :
382.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJEMAG Japanese Journal of Experimental Medicine. (Kinokuniya Book-Stores of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581 Webster St., San Francisco, CA 94115) V.7- 1928- Volume(issue)/page/year: 42,187,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
24870 ug/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)
REFERENCE :
AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300 + H310 + H330
Precautionary Statements P260-P264-P280-P284-P301 + P310-P302 + P350
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+,Xn,F
Risk Phrases 26/27/28-36-20/21/22-11
Safety Phrases 22-36/37/39-45-36/37-16-26
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS YD0080000
Packaging Group I
Hazard Class 6.1(a)

 Synthetic Route

~38%

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

~14%

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

~%

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589
Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

~%

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

~%

Neosolaniol Structure

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

 Articles16

More Articles
Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers.

Food Chem. Toxicol. 74 , 120-30, (2014)

The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently suppl...

Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins.

PLoS ONE 10(4) , e0124204, (2015)

Shc proteins interact with the insulin receptor, indicating a role in regulating glycolysis. To investigate this idea, the activities of key glycolytic regulatory enzymes and metabolites levels were m...

Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport.

Proc. Natl. Acad. Sci. U. S. A. 112(1) , 142-7, (2015)

The segregation of approximately two dozen distinct mRNAs from yeast mother to daughter cell cytoplasm is a classical paradigm for eukaryotic mRNA transport. The information for transport resides in a...

 Synonyms

Trichothec-9-ene, 12,13-epoxy-4-β,15-diacetoxy-3-α,8-α-dihydroxy-
4-β,15-Diacetoxy-3-α,8-α-dihydroxy-12,13-epoxytrichothec-9-ene
Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 4,15-diacetate
(3α,4β,8α)-3,8-Dihydroxy-12,13-epoxytrichothec-9-ene-4,15-diyl diacetate
Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate, (3α,4β,8α)-
Solaniol (van)
8-HYDROXYDIACETOXYSCIRPENOL
neosolaniol solution
Neosalaniol
NEOSOLANIOL
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Neosolaniol suppliers

Neosolaniol price