3-hydroxy-9H-9-xanthenone

Modify Date: 2024-01-09 11:49:41

3-hydroxy-9H-9-xanthenone Structure
3-hydroxy-9H-9-xanthenone structure
 Common Name 3-hydroxy-9H-9-xanthenone
CAS Number 3722-51-8 Molecular Weight 212.20
Density 1.4±0.1 g/cm3 Boiling Point 403.9±24.0 °C at 760 mmHg
Molecular Formula C13H8O3 Melting Point 243 °C
MSDS N/A Flash Point 162.9±16.4 °C

 Use of 3-hydroxy-9H-9-xanthenone


3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs). 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].

 Names

Name 3-Hydroxyxanthen-9-one
Synonym More Synonyms

 3-hydroxy-9H-9-xanthenone Biological Activity

Description 3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs). 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].
Related Catalog
References

[1]. Madan B, et al. Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs). Bioorg Med Chem. 2002 Nov;10(11):3431-6.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 403.9±24.0 °C at 760 mmHg
Melting Point 243 °C
Molecular Formula C13H8O3
Molecular Weight 212.20
Flash Point 162.9±16.4 °C
Exact Mass 212.047348
PSA 50.44000
LogP 2.83
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.679
Storage condition Store at 0°C

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S16-S26-S36/37/39-S37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 29329900

 Synthetic Route

 Synonyms

MFCD06796485
3-hydroxy-9H-9-xanthenone
Sieber Linker; 3-Hydroxy-xanthen-9-one
3-hydroxyxanthen-9-one
3-Hydroxy-9H-xanthen-9-one
9H-Xanthen-9-one, 3-hydroxy-
Xanthen-9-one, 3-hydroxy-
Sieber Linker
Weinreb Linker
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