2,2'-Cyclouridine

Modify Date: 2024-01-02 12:15:21

2,2'-Cyclouridine Structure
2,2'-Cyclouridine structure
Common Name 2,2'-Cyclouridine
CAS Number 3736-77-4 Molecular Weight 226.186
Density 2.0±0.1 g/cm3 Boiling Point 456.3±55.0 °C at 760 mmHg
Molecular Formula C9H10N2O5 Melting Point 239-240ºC
MSDS USA Flash Point 229.8±31.5 °C

 Use of 2,2'-Cyclouridine


2,2'-Anhydrouridine is used for anticancer and antiviral research[1].

 Names

Name 2,2'-O-Anhydro-(1-β-D-arabinofuranosyl)uracil
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 456.3±55.0 °C at 760 mmHg
Melting Point 239-240ºC
Molecular Formula C9H10N2O5
Molecular Weight 226.186
Flash Point 229.8±31.5 °C
Exact Mass 226.058975
PSA 93.81000
LogP -1.40
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.816
Storage condition Store at RT.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29349990

 Synthetic Route

 Articles5

More Articles
2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, a cyclouridine nucleoside with a C4'-endo furanosyl conformation.

Acta Crystallogr. C 69(Pt 3) , 282-4, (2013)

2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, C13H14N2O7, was obtained by refluxing 2',3'-O-(methoxymethylene)uridine in acetic anhydride. The structure exhibits a nearly perfect C4'-...

Aldrichimica Acta 20 , 52, (1987)

Inhibitor properties of some 5-substituted uracil acyclonucleosides, and 2,2'-anhydrouridines versus uridine phosphorylase from E. coli and mammalian sources.

Biochem. Pharmacol. 36(23) , 4125-8, (1987)

Two series of 5-substituted uracil N(1)-acyclonucleosides, each with a different acyclic chain, were examined as inhibitors of uridine phosphorylase from rat intestinal mucosa, and several against the...

 Synonyms

O2,2'-Cyclouridine
EINECS 223-107-6
2,2'-Cyclouridine
2,2'-O-Cyclouridine
MFCD00004945
2,2-Anhydro-1(b-D-arabinofuranosyl)uracil
2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil
2,2′-O-Cyclouridine
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3R,3aS,9aR)-
O2,2'-Cyclouridine (VAN)
(2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
2,2'-Anhydrouridine
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