2'-Azido-2'-deoxyuridine

Modify Date: 2024-01-12 16:31:37

2'-Azido-2'-deoxyuridine Structure
2'-Azido-2'-deoxyuridine structure
Common Name 2'-Azido-2'-deoxyuridine
CAS Number 26929-65-7 Molecular Weight 269.214
Density N/A Boiling Point N/A
Molecular Formula C9H11N5O5 Melting Point 149-153ºC
MSDS N/A Flash Point N/A

 Use of 2'-Azido-2'-deoxyuridine


2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1].

 Names

Name 2′-Azido-2′-deoxyuridine
Synonym More Synonyms

 2'-Azido-2'-deoxyuridine Biological Activity

Description 2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1].
Related Catalog
In Vitro 2'-Azido-2'-deoxyuridine (N3dUrd) has IC50s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell[1].
References

[1]. Kang SH, et al. Biological activity and phosphorylation of 2'-azido-2'-deoxyuridine and 2'-azido-2'-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88.

 Chemical & Physical Properties

Melting Point 149-153ºC
Molecular Formula C9H11N5O5
Molecular Weight 269.214
Exact Mass 269.076019
PSA 154.30000
LogP -1.10
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Uridine, 2'-azido-2'-deoxy-
2'-Azido-2'-deoxyuridine
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