3’-Deoxy-3’-α-C-methyl-5-fluorouridine

Modify Date: 2024-01-02 16:48:30

3’-Deoxy-3’-α-C-methyl-5-fluorouridine Structure
3’-Deoxy-3’-α-C-methyl-5-fluorouridine structure
Common Name 3’-Deoxy-3’-α-C-methyl-5-fluorouridine
CAS Number 37731-67-2 Molecular Weight 260.22
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Deoxy-3’-α-C-methyl-5-fluorouridine


3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Deoxy-5-fluoro-3'-methyluridine
Synonym More Synonyms

  Biological Activity

Description 3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C10H13FN2O5
Molecular Weight 260.22
Exact Mass 260.080841
LogP -0.96
Index of Refraction 1.593

 Synonyms

Uridine, 3'-deoxy-5-fluoro-3'-methyl-
3'-Deoxy-5-fluoro-3'-methyluridine