5-Methoxy-4-thiouridine

Modify Date: 2024-01-11 20:07:27

5-Methoxy-4-thiouridine Structure
5-Methoxy-4-thiouridine structure
Common Name 5-Methoxy-4-thiouridine
CAS Number 37805-89-3 Molecular Weight 290.29
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H14N2O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methoxy-4-thiouridine


5-Methoxy-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Synonym More Synonyms

 5-Methoxy-4-thiouridine Biological Activity

Description 5-Methoxy-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C10H14N2O6S
Molecular Weight 290.29
Exact Mass 290.057251
LogP 0.07
Index of Refraction 1.695

 Synonyms

5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 3,4-dihydro-5-methoxy-1-β-D-ribofuranosyl-4-thioxo-