4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-pyrimidin-2-one

Modify Date: 2024-04-09 11:53:33

4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-pyrimidin-2-one Structure
4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-pyrimidin-2-one structure
Common Name 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-pyrimidin-2-one
CAS Number 37805-90-6 Molecular Weight 273.24
Density 1.81g/cm3 Boiling Point 569.9ºC at 760 mmHg
Molecular Formula C10H15N3O6 Melting Point N/A
MSDS N/A Flash Point 298.4ºC

 Use of 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-pyrimidin-2-one


5-Methoxy cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidin-2-one
Synonym More Synonyms

  Biological Activity

Description 5-Methoxy cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Density 1.81g/cm3
Boiling Point 569.9ºC at 760 mmHg
Molecular Formula C10H15N3O6
Molecular Weight 273.24
Flash Point 298.4ºC
Exact Mass 273.09600
PSA 140.06000
Index of Refraction 1.706
Storage condition 2-8°C

 Synonyms

5-methoxy-cytidine
5-Methoxycytidin