Nepodin
Modify Date: 2024-01-10 14:22:09
Nepodin structure
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Common Name | Nepodin | ||
|---|---|---|---|---|
| CAS Number | 3785-24-8 | Molecular Weight | 216.233 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 413.2±40.0 °C at 760 mmHg | |
| Molecular Formula | C13H12O3 | Melting Point | 165-166℃ (methanol ) | |
| MSDS | N/A | Flash Point | 217.8±23.8 °C | |
Use of NepodinNepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus[1].Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK[2].Nepodin (Musizin) has antidiabetic and antimalarial activities. |
| Name | 1-(1,8-dihydroxy-3-methylnaphthalen-2-yl)ethanone |
|---|---|
| Synonym | More Synonyms |
| Description | Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus[1].Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK[2].Nepodin (Musizin) has antidiabetic and antimalarial activities. |
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| Related Catalog | |
| In Vitro | Nepodin (Musizin) exhibits significant IC50 values that are 0.74 and 0.79 μg/ml against P. falciparum chloroquine-sensitive (3D7) and P. falciparum chloroquine-resistant (S20), respectively[1]. |
| In Vivo | Nepodin (Musizin) (orally administration; 2-10 mg/kg; 4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner[2]. Animal Model: C57BL/KsJ-db/db mice[2] Dosage: 2 mg/kg; 10 mg/kg Administration: Orally administration; 2-10 mg/kg; 4 weeks Result: Had antihyperglycemic potential and improved insulin resistance. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 413.2±40.0 °C at 760 mmHg |
| Melting Point | 165-166℃ (methanol ) |
| Molecular Formula | C13H12O3 |
| Molecular Weight | 216.233 |
| Flash Point | 217.8±23.8 °C |
| Exact Mass | 216.078644 |
| PSA | 57.53000 |
| LogP | 2.87 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.668 |
| HS Code | 2914400090 |
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|
~87%
Nepodin CAS#:3785-24-8 |
| Literature: Rizzacasa, Mark A.; Sargent, Melvyn V. Australian Journal of Chemistry, 1988 , vol. 41, # 7 p. 1087 - 1097 |
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~%
Nepodin CAS#:3785-24-8 |
| Literature: Rizzacasa, Mark A.; Sargent, Melvyn V. Australian Journal of Chemistry, 1988 , vol. 41, # 7 p. 1087 - 1097 |
| Precursor 2 | |
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| DownStream 1 | |
| HS Code | 2914400090 |
|---|---|
| Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
| Ethanone, 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)- |
| Dianellidin |
| dianellidine |
| 1,8-dihydroxy-2-acetyl-3-methylnaphthalene |
| 1-(1,8-Dihydroxy-3-methyl-2-naphthyl)ethanone |
| 1-(1,8-Dihydroxy-3-methyl-2-naphthalenyl)ethanone |
| Musizin |
| 2-acetyl-1,8-dihydroxy-3-methylnaphthalene |
| Nepodin |
- BioBioPha
- China
- Product Name: Nepodin
- Price: ￥1000.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Nepodin
- Price: ￥1600.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Nepodin
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Ethanone,1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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Price: ￥1340/1 mg
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