2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2024-01-03 17:32:29

2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Structure
2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure
Common Name 2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
CAS Number 3868-34-6 Molecular Weight 297.27
Density 2.29g/cm3 Boiling Point 748.8ºC at 760 mmHg
Molecular Formula C10H15N7O4 Melting Point N/A
MSDS N/A Flash Point 406.7ºC

 Use of 2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol


8-Hydrazinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-(6-amino-8-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

  Biological Activity

Description 8-Hydrazinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.29g/cm3
Boiling Point 748.8ºC at 760 mmHg
Molecular Formula C10H15N7O4
Molecular Weight 297.27
Flash Point 406.7ºC
Exact Mass 297.11900
PSA 177.59000
Index of Refraction 2.002

 Synonyms

8-Hydrazinoadenosin
8-hydrazino-adenosine
8-hydrazinyl-9-pentofuranosyl-9h-purin-6-amine