Somatostatin-14
Somatostatin-14 structure
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Common Name | Somatostatin-14 | ||
|---|---|---|---|---|
| CAS Number | 38916-34-6 | Molecular Weight | 1637.878 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1970.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C76H104N18O19S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 1145.7±34.3 °C | |
Use of Somatostatin-14Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14). |
| Name | somatostatin |
|---|---|
| Synonym | More Synonyms |
| Description | Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14). |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1970.9±65.0 °C at 760 mmHg |
| Molecular Formula | C76H104N18O19S2 |
| Molecular Weight | 1637.878 |
| Flash Point | 1145.7±34.3 °C |
| Exact Mass | 1636.716675 |
| PSA | 663.83000 |
| LogP | -4.25 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.670 |
| Storage condition | −20°C |
| Water Solubility | H2O: 1 mg/mL | Soluble in water(25,00°C 1,00 g/L), Methanol. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | WF8751700 |
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~95%
Somatostatin-14 CAS#:38916-34-6 |
| Literature: Kitada, Shingo; Takahashi, Masahito; Yamaguchi, Yusuke; Okada, Yohei; Chiba, Kazuhiro Organic Letters, 2012 , vol. 14, # 23 p. 5960 - 5963 |
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~%
Somatostatin-14 CAS#:38916-34-6 |
| Literature: Shi, Tiesheng; Rabenstein, Dallas L. Journal of Organic Chemistry, 1999 , vol. 64, # 13 p. 4590 - 4595 |
| Precursor 1 | |
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| DownStream 0 | |
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Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.
J. Neurosci. 34(35) , 11769-80, (2014) Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hip... |
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Role of somatostatin and somatostatin receptor type 2 in postincisional nociception in rats.
Neuropeptides 49 , 47-54, (2015) Somatostatin (SST) and the somatostatin receptor type 2 (sstr2) are expressed in the superficial part (Laminae I-III) of the dorsal horn of the spinal cord. Since the neurons in these laminae also rec... |
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Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration.
BMC Biol. 13 , 70, (2015) In contrast to mammals, the zebrafish has the remarkable capacity to regenerate its pancreatic beta cells very efficiently. Understanding the mechanisms of regeneration in the zebrafish and the differ... |
| growth hormone inhibiting hormone |
| 15-28-Somatostatin-28 |
| Modustatina |
| SS-14 |
| L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide |
| Somatostatin Acetate |
| Somatofalk |
| MFCD00076762 |
| Stilamin |
| GH-RIF |
| SRIF-A |
| somatotropin release inhibiting factor |
| L-Alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine Cyclic (3®14) Disulfide |
| SRIF |
| Somatostatin |
| Somatostatina |
| EINECS 256-969-7 |
| Aminopan |
| L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide |
| Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]- |
| Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]- |
| ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS: AGCKNFFWKTFTSC DISULFIDE BRIDGE CYS3-CYS14 |
| Cyclic somatostatin |
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