58976-46-8

58976-46-8 structure

Name: (D-Trp8)-Somatostatin-14 trifluoroacetate salt
Chemical Name: ala-gly-cys-lys-asn-phe-phe-d-trp-lys-thr-phe-thr-ser-cys
CAS Number: 58976-46-8
Molecular Formula: C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight: 1637.878
Catalog: Research Areas Neurological Disease
Create Date: 2017-07-20 13:38:49
Modify Date: 2024-01-07 08:46:53
[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin[1].

Name	ala-gly-cys-lys-asn-phe-phe-d-trp-lys-thr-phe-thr-ser-cys
Synonyms	M.W. 686.90 C33H46N6O10 D-Ser2,Leu5,Thr6-enkephalin Dislet Dstle TYR-D-SER-GLY-PHE-LEU-THR L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]- 2-Ser-Thr-Leu-enkephalin (D-Trp8)-Somatostatin-14 [D-Trp8]-Somatostatin-14

Description	[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	[D-Trp8] Somatostatin-14 抑制生长激素、胰高血糖素和胰岛素释放的效力是 Somatostatin 的 6-8 倍[1]。
References	[1]. J Rivier, et al. D-Trp8-somatostatin: an analog of somatostatin more potent than the native molecule. Biochem Biophys Res Commun. 1975 Jul 22;65(2):746-51.