rosoxacin

Modify Date: 2024-01-09 10:33:20

rosoxacin Structure
rosoxacin structure
Common Name rosoxacin
CAS Number 40034-42-2 Molecular Weight 294.30500
Density 1.317g/cm3 Boiling Point 500.8ºC at 760 mmHg
Molecular Formula C17H14N2O3 Melting Point 290°
MSDS N/A Flash Point 256.7ºC

 Use of rosoxacin


Rosoxacin (Acrosoxacin) is a potent and orally active quinolone antibiotic. Rosoxacin (Acrosoxacin) has antibacterial activities against a broad spectrum of Gram negative bacteria including Neisseria gonorrhoeae (MIC90=0.03mg/ml). Rosoxacin has the potential for urinary tract infections treatment[1].

 Names

Name 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
Synonym More Synonyms

 rosoxacin Biological Activity

Description Rosoxacin (Acrosoxacin) is a potent and orally active quinolone antibiotic. Rosoxacin (Acrosoxacin) has antibacterial activities against a broad spectrum of Gram negative bacteria including Neisseria gonorrhoeae (MIC90=0.03mg/ml). Rosoxacin has the potential for urinary tract infections treatment[1].
Related Catalog
Target

MIC90: 0.03 mg/ml[1]

References

[1]. Lim KB, et al. Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).Br J Vener Dis. 1984 Jun;60(3):157-60.

 Chemical & Physical Properties

Density 1.317g/cm3
Boiling Point 500.8ºC at 760 mmHg
Melting Point 290°
Molecular Formula C17H14N2O3
Molecular Weight 294.30500
Flash Point 256.7ºC
Exact Mass 294.10000
PSA 72.19000
LogP 2.78160
Index of Refraction 1.633

 Safety Information

HS Code 2933990090

 Synthetic Route

~87%

rosoxacin Structure

rosoxacin

CAS#:40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

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rosoxacin Structure

rosoxacin

CAS#:40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

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rosoxacin Structure

rosoxacin

CAS#:40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

~%

rosoxacin Structure

rosoxacin

CAS#:40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Rosoxacinum
Eracine
1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
1,4-Dihydro-1-ethyl-7-(4-pyridinyl)-4-oxo-3quinolinecarboxylic acid
Rosoxacino
Roxadyl
Eradacin
Eradacil
Rosoxacine
Acrosoxacin
ROSOXACIN
1-ethyl-1,4-dihydro-4-oxo-7-(pyridin-4-yl)-3-quinolinecarboxylic acid
Winuron
1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinoxalinecarboxylic acid
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