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40034-42-2

40034-42-2 structure
40034-42-2 structure
  • Name: rosoxacin
  • Chemical Name: 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
  • CAS Number: 40034-42-2
  • Molecular Formula: C17H14N2O3
  • Molecular Weight: 294.30500
  • Catalog: API Synthetic anti-infective drugs Quinolone
  • Create Date: 2018-06-23 11:03:39
  • Modify Date: 2024-01-09 10:33:20
  • Rosoxacin (Acrosoxacin) is a potent and orally active quinolone antibiotic. Rosoxacin (Acrosoxacin) has antibacterial activities against a broad spectrum of Gram negative bacteria including Neisseria gonorrhoeae (MIC90=0.03mg/ml). Rosoxacin has the potential for urinary tract infections treatment[1].

Name 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
Synonyms Rosoxacinum
Eracine
1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
1,4-Dihydro-1-ethyl-7-(4-pyridinyl)-4-oxo-3quinolinecarboxylic acid
Rosoxacino
Roxadyl
Eradacin
Eradacil
Rosoxacine
Acrosoxacin
ROSOXACIN
1-ethyl-1,4-dihydro-4-oxo-7-(pyridin-4-yl)-3-quinolinecarboxylic acid
Winuron
1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinoxalinecarboxylic acid
Description Rosoxacin (Acrosoxacin) is a potent and orally active quinolone antibiotic. Rosoxacin (Acrosoxacin) has antibacterial activities against a broad spectrum of Gram negative bacteria including Neisseria gonorrhoeae (MIC90=0.03mg/ml). Rosoxacin has the potential for urinary tract infections treatment[1].
Related Catalog
Target

MIC90: 0.03 mg/ml[1]

References

[1]. Lim KB, et al. Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).Br J Vener Dis. 1984 Jun;60(3):157-60.

Density 1.317g/cm3
Boiling Point 500.8ºC at 760 mmHg
Melting Point 290°
Molecular Formula C17H14N2O3
Molecular Weight 294.30500
Flash Point 256.7ºC
Exact Mass 294.10000
PSA 72.19000
LogP 2.78160
Index of Refraction 1.633
HS Code 2933990090

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40034-42-2 structure

40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

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40034-42-2 structure

40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

~%

40034-42-2 structure

40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863

~%

40034-42-2 structure

40034-42-2

Literature: Carabateas; Brundage; Gelotte; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1857 - 1863
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%