15-Keto Travoprost

Modify Date: 2024-01-03 08:40:20

15-Keto Travoprost Structure
15-Keto Travoprost structure
Common Name 15-Keto Travoprost
CAS Number 404830-45-1 Molecular Weight 498.532
Density 1.2±0.1 g/cm3 Boiling Point 577.5±50.0 °C at 760 mmHg
Molecular Formula C26H33F3O6 Melting Point N/A
MSDS N/A Flash Point 303.1±30.1 °C

 Use of 15-Keto Travoprost


15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes[1][2].

 Names

Name propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate
Synonym More Synonyms

 15-Keto Travoprost Biological Activity

Description 15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes[1][2].
Related Catalog
In Vitro 15-Keto Travoprost (80 µgr/mL) can be used for the treatment of idiopathic hypotrichosis of the eyelashes[1].
References

[1]. Fabbrocini G, et al. 15 keto fluprostenol isopropyl ester (80 µgr/mL) gel for cosmetic eyelash growth and enhancement. J Cosmet Dermatol. 2019 Apr;18(2):545-549.

[2]. Ciro C, et al. Effect of Fluprostenol Isopropyl Ester and 15-Keto Fluprostenol on Eyelash Growth: A Clinical and Pharmacologic Study. Skinmed. 2018 Jul 1;16(4):231-233.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 577.5±50.0 °C at 760 mmHg
Molecular Formula C26H33F3O6
Molecular Weight 498.532
Flash Point 303.1±30.1 °C
Exact Mass 498.222931
PSA 93.06000
LogP 3.82
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.541

 Synonyms

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-
Travoprost impurity,15-keto derivative-[USP]
UNII-4U2P9U9Z66
Isopropyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate
15-Oxo travoprost
15-keto Fluprostenol isopropyl ester
15-Keto Travoprost
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester
(5Z,13E)-(9S,11R)-9,11,-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid,isopropyl ester
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