NFPS
Modify Date: 2024-01-13 20:00:53
NFPS structure
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Common Name | NFPS | ||
|---|---|---|---|---|
| CAS Number | 405225-21-0 | Molecular Weight | 393.45100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24FNO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NFPSNFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively[1]. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion[2]. |
| Name | 2-[[3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively[1]. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion[2]. |
|---|---|
| Related Catalog | |
| Target |
hGlyT1:2.8 nM (IC50) rGlyT1:9.8 nM (IC50) |
| References |
| Molecular Formula | C24H24FNO3 |
|---|---|
| Molecular Weight | 393.45100 |
| Exact Mass | 393.17400 |
| PSA | 49.77000 |
| LogP | 5.01930 |
| alx5407 |
| nfps |