Medioresil

Modify Date: 2024-01-07 10:47:27

Medioresil structure	Common Name	Medioresil
	CAS Number	40957-99-1	Molecular Weight	388.411
	Density	1.3±0.1 g/cm3	Boiling Point	575.7±50.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	302.0±30.1 °C

Use of Medioresil

(+)-Medioresinol is a furofuran type lignan with antifungal, antibacterial and lesishmanicidal activities. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. (+)-Medioresinol can reduce the cardiovascular disease risk[1][2].

Name	4-[(1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H- furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenol
Synonym	More Synonyms

Description	(+)-Medioresinol is a furofuran type lignan with antifungal, antibacterial and lesishmanicidal activities. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. (+)-Medioresinol can reduce the cardiovascular disease risk[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Ji Hong Hwang, et al. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. Biochimie. 2012 Aug;94(8):1784-93. [2]. Ji Hong Hwang, et al. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro. Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cardiovascular Disease

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Neurological Disease

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Ji Hong Hwang, et al. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. Biochimie. 2012 Aug;94(8):1784-93.

[2]. Ji Hong Hwang, et al. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro. Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41.

Density	1.3±0.1 g/cm3
Boiling Point	575.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₄O₇
Molecular Weight	388.411
Flash Point	302.0±30.1 °C
Exact Mass	388.152191
PSA	86.61000
LogP	1.12
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.587