14-Deoxyandrographolide structure
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Common Name | 14-Deoxyandrographolide | ||
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CAS Number | 4176-97-0 | Molecular Weight | 334.45000 | |
Density | 1.15g/cm3 | Boiling Point | 509.5ºC at 760 mmHg | |
Molecular Formula | C20H30O4 | Melting Point | 176-178ºC | |
MSDS | USA | Flash Point | 177.3ºC |
Use of 14-Deoxyandrographolide14-Deoxyandrographolide, a bioactive compound of Andrographis paniculata, has hepatoprotective efficacy. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release[1]. |
Name | 3-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethy l-2-methylenedecahydro-1-naphthalenyl]ethyl}-2(5H)-furanone |
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Synonym | More Synonyms |
Description | 14-Deoxyandrographolide, a bioactive compound of Andrographis paniculata, has hepatoprotective efficacy. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release[1]. |
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Related Catalog | |
References |
Density | 1.15g/cm3 |
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Boiling Point | 509.5ºC at 760 mmHg |
Melting Point | 176-178ºC |
Molecular Formula | C20H30O4 |
Molecular Weight | 334.45000 |
Flash Point | 177.3ºC |
Exact Mass | 334.21400 |
PSA | 66.76000 |
LogP | 2.99180 |
Index of Refraction | 1.551 |
Storage condition | 2-8℃ |
~82% 14-Deoxyandrogr... CAS#:4176-97-0 |
Literature: Pandeti, Sukanya; Sonkar, Ravi; Shukla, Astha; Bhatia, Gitika; Tadigoppula, Narender European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 439 - 448 |
~% 14-Deoxyandrogr... CAS#:4176-97-0 |
Literature: Pal, Mahesh; Singh, Meenakshi; Sharma Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 9 p. 1915 - 1918 |
~2% 14-Deoxyandrogr... CAS#:4176-97-0 |
Literature: Fujita, Tetsuro; Fujitani, Ryujiro; Takeda, Yoshio; Takaishi, Yoshihisa; Yamada, Toshihide; et al Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2117 - 2125 |
Precursor 1 | |
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DownStream 1 | |
20-ethyl-7,8-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-one |
14-Dehydro-browniin |
14-Dehydrobrowniine |
Aconitan-14-one,20-ethyl-7,8-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-,(1alpha,6beta,16beta) |
14-deoxy andrographolide |
Dehydrobrowniin |
10-Dehydro-browniin |
3-(2-((1R,4aS,5R,6R,8aS)-6-hydroxyl-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)ethyl)furan-2(5H)-one |
Deoxyandrographolide |