EGFR/HER2/CDK9-IN-3

Modify Date: 2024-08-05 13:13:17

EGFR/HER2/CDK9-IN-3 structure	Common Name	EGFR/HER2/CDK9-IN-3
	CAS Number	422276-47-9	Molecular Weight	479.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁N₃O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR/HER2/CDK9-IN-3

EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity[1].

Name	EGFR/HER2/CDK9-IN-3

Description	EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
References	[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

Molecular Formula	C₂₄H₂₁N₃O₄S₂
Molecular Weight	479.57