Triadimefon

Modify Date: 2024-01-02 10:21:25

Triadimefon Structure
Triadimefon structure
Common Name Triadimefon
CAS Number 43121-43-3 Molecular Weight 293.749
Density 1.2±0.1 g/cm3 Boiling Point 441.9±55.0 °C at 760 mmHg
Molecular Formula C14H16ClN3O2 Melting Point 82°C
MSDS Chinese USA Flash Point 221.0±31.5 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of Triadimefon


Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.

 Names

Name triadimefon
Synonym More Synonyms

 Triadimefon Biological Activity

Description Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 441.9±55.0 °C at 760 mmHg
Melting Point 82°C
Molecular Formula C14H16ClN3O2
Molecular Weight 293.749
Flash Point 221.0±31.5 °C
Exact Mass 293.093109
PSA 57.01000
LogP 2.77
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.580
Water Solubility 0.026 G/100 ML

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL7100000
CHEMICAL NAME :
2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-y l)-
CAS REGISTRY NUMBER :
43121-43-3
BEILSTEIN REFERENCE NO. :
0619231
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C14-H16-Cl-N3-O2
MOLECULAR WEIGHT :
293.78
WISWESSER LINE NOTATION :
T5NN DNJ AYOR DG&VX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
363 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2450 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2337 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5800 ug/m3/17W-I
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Blood - methemoglobinemia-carboxyhemoglobin Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5800 ug/m3/17W-I
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Blood - methemoglobinemia-carboxyhemoglobin Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,157,1995 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H317-H410
Precautionary Statements P280-P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn,N,T,F
Risk Phrases R22
Safety Phrases 24-37-61-45-36/37
RIDADR 2588
WGK Germany 3
RTECS EL7100000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933990014

 Synthetic Route

~66%

Triadimefon Structure

Triadimefon

CAS#:43121-43-3

Literature: RALLIS INDIA LTD.; KAMARAJ, Pasumpon; SATAM, Vijay, Shrikant; AJJANNA, Mahalingappa, Sridhara; NANDI, Tapaskumar; BOBADE, Anna; SHINDE, Ravindra; NAIK, Parag; MOHITE, Dhanaji; KADAM, Subhash; HINDUPUR, Rama, Mohan; PATI, Hari, Narayan; MANE, Avinash; VADIRAJ, Suphala, Gopinath; VENKATESH, Prabhu, Moodbidri Patent: WO2013/144924 A1, 2013 ; Location in patent: Page/Page column 33; 34 ;

~%

Triadimefon Structure

Triadimefon

CAS#:43121-43-3

Literature: RALLIS INDIA LTD.; KAMARAJ, Pasumpon; SATAM, Vijay, Shrikant; AJJANNA, Mahalingappa, Sridhara; NANDI, Tapaskumar; BOBADE, Anna; SHINDE, Ravindra; NAIK, Parag; MOHITE, Dhanaji; KADAM, Subhash; HINDUPUR, Rama, Mohan; PATI, Hari, Narayan; MANE, Avinash; VADIRAJ, Suphala, Gopinath; VENKATESH, Prabhu, Moodbidri Patent: WO2013/144924 A1, 2013 ;

 Customs

HS Code 2933990014
Summary 2933990014 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1h-1,2,4-triazol-1-yl)butan-2-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles32

More Articles
Is the amphibian X. laevis WEC a good alternative method to rodent WEC teratogenicity assay? The example of the three triazole derivative fungicides Triadimefon, Tebuconazole, Cyproconazole.

Reprod. Toxicol. 32(2) , 220-6, (2011)

The aim of the present work is the assessment of teratogenic effects of three triazole-derived fungicides (Triadimefon, FON, Tebuconazole, TEBU, Cyproconazole, CYPRO) on rat and Xenopus laevis embryos...

Stage-dependent abnormalities induced by the fungicide triadimefon in the mouse.

Reprod. Toxicol. 31(2) , 194-9, (2011)

Aim of this work is the study of abnormalities induced by the triazole triadimefon (FON) administered to pregnant mice at E8, E9, E10, E11 or E12. Pregnant CD-1 mouse were gavaged with FON 500 mg/kg a...

Changes of thyroid hormone levels and related gene expression in zebrafish on early life stage exposure to triadimefon.

Environ. Toxicol. Pharmacol. 32(3) , 472-7, (2011)

In this study, zebrafish was exposed to triadimefon. Thyroid hormones levels and the expression of related genes in the hypothalamic-pituitary-thyroid (HPT) axis, including thyroid-stimulating hormone...

 Synonyms

2-Butanone, 1- (4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-
Triadimefone
UNII:1HW039CJF0
Triadimeform
MILTEK
MFCD00055506
1-(4-Chlorphenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-on
2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-
ACIZOL
BAY 6681F
1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one
1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one
BAY 6681 F
BAY-MEB-6447
Bay MEB 6447
Fenxiunin
SAMETON
ROFON
Azocene
1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone
OTRIA
EINECS 256-103-8
(RS)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one
NUREX
DAYTON
Triadimefon
Amiral
TYPHON
rac-(1R)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one
Top Suppliers:I want be here





Get all suppliers and price by the below link:

Triadimefon suppliers

Triadimefon price