(3β)-7-Dehydro Cholesterol

Modify Date: 2024-01-02 19:39:34

(3β)-7-Dehydro Cholesterol Structure
(3β)-7-Dehydro Cholesterol structure
Common Name (3β)-7-Dehydro Cholesterol
CAS Number 434-16-2 Molecular Weight 384.638
Density 1.0±0.1 g/cm3 Boiling Point 493.7±34.0 °C at 760 mmHg
Molecular Formula C27H44O Melting Point 148-152 °C(lit.)
MSDS Chinese USA Flash Point 212.3±17.9 °C

 Use of (3β)-7-Dehydro Cholesterol


7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

 Names

Name cholesta-5,7-dien-3β-ol
Synonym More Synonyms

 (3β)-7-Dehydro Cholesterol Biological Activity

Description 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen[1].
References

[1]. Xu L, et al. Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies. J Am Chem Soc. 2010 Feb 24;132(7):2222-32.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 493.7±34.0 °C at 760 mmHg
Melting Point 148-152 °C(lit.)
Molecular Formula C27H44O
Molecular Weight 384.638
Flash Point 212.3±17.9 °C
Exact Mass 384.339203
PSA 20.23000
LogP 9.46
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.536
Storage condition -20℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FZ5650000
CHEMICAL NAME :
Cholesta-5,7-dien-3-beta-ol
CAS REGISTRY NUMBER :
434-16-2
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C27-H44-O
MOLECULAR WEIGHT :
384.71
WISWESSER LINE NOTATION :
L E5 B666 JU LUTJ A1 E1 FY1&3Y1&1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 gm/kg/2W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 60,525,1973

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS FZ5650000

 Synthetic Route

 Articles57

More Articles
Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.

PLoS ONE 4(4) , e5182, (2009)

Activation of Hedgehog (Hh) signaling requires the transmembrane protein Smoothened (Smo), a member of the G-protein coupled receptor superfamily. In mammals, Smo translocates to the primary cilium up...

Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry.

J. Chromatogr. A. 1364 , 214-22, (2014)

We have developed an ultra-high-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometric (UHPLC-APPI-MS/MS) method for the simultaneous quantitative analyses of...

The Essential Role of Cholesterol Metabolism in the Intracellular Survival of Mycobacterium leprae Is Not Coupled to Central Carbon Metabolism and Energy Production.

J. Bacteriol. 197 , 3698-707, (2015)

Mycobacterium leprae induces the formation of lipid droplets, which are recruited to pathogen-containing phagosomes in infected macrophages and Schwann cells. Cholesterol is among the lipids with incr...

 Synonyms

delta7-Cholesterol
(3b)-7-Dehydrocholesterol
Cholesta-5,7-dien-3-ol, (3β)-
Cholesta-5,7-dien-3β-ol (8CI)
Cholesta-5,7-dien-3-β-ol
Provitamin D3
EINECS 207-100-5
Dehydrocholesterol
(3Beta)-7-Dehydro Cholesterol
(3b)-Cholesta-5,7-dien-3-ol
3β-Hydroxy-5,7-cholestadiene
Provitamine
cholesta-5,7-dien-3beta-ol
(-)-7-dehydrocholesterol
Dehydrocholesterin
(3β)-Cholesta-5,7-dien-3-ol
5,7-Cholestadien-3β-ol
7-DHC
7-Dehydrocholesterol
Provitamin D(sub 3)
MFCD00003624
Cholesta-5,7-dien-3β-ol
cholesta-5,7-dien-3b-ol
(3β)-7-Dehydrocholesterol
Top Suppliers:I want be here





Get all suppliers and price by the below link:

(3β)-7-Dehydro Cholesterol suppliers


Price: ¥600/100 mg

Reference only. check more (3β)-7-Dehydro Cholesterol price