LDN 91946

Modify Date: 2024-01-10 17:27:35

LDN 91946 Structure
LDN 91946 structure
Common Name LDN 91946
CAS Number 439946-22-2 Molecular Weight 314.316
Density 1.6±0.1 g/cm3 Boiling Point 714.0±60.0 °C at 760 mmHg
Molecular Formula C17H12N6O Melting Point N/A
MSDS Chinese USA Flash Point 385.6±32.9 °C

 Use of LDN 91946


LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).

 Names

Name LDN-91946
Synonym More Synonyms

 LDN 91946 Biological Activity

Description LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).
References References 1. Mermerian AH, et al. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32. 2. Coulombe J, et al. Front Aging Neurosci. 2014 Jun 19;6:129. View Related Products by Target Deubiquitinase (DUB)

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 714.0±60.0 °C at 760 mmHg
Molecular Formula C17H12N6O
Molecular Weight 314.316
Flash Point 385.6±32.9 °C
Exact Mass 314.036133
LogP 2.20
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.722

 Synonyms

3-Amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acid
Thieno[2,3-b]pyridine-5-carboxylic acid, 3-amino-2-benzoyl-6,7-dihydro-6-oxo-
LDN-91946
MFCD03016619
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