3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine

Modify Date: 2024-10-12 17:48:40

3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine Structure
3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine structure
Common Name 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
CAS Number 4402-18-0 Molecular Weight 416.48
Density 1.4±0.1 g/cm3 Boiling Point 835.8±75.0 °C at 760 mmHg
Molecular Formula C26H20N6 Melting Point N/A
MSDS Chinese USA Flash Point 503.4±24.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine


DDRI-18 is a DNA damage response inhibitor that inhibits the non-homologous end-joining (NHEJ) DNA repair process. DDRI-18 is an effective chemosensitizing agent[1].

 Names

Name DDRI-18
Synonym More Synonyms

  Biological Activity

Description DDRI-18 is a DNA damage response inhibitor that inhibits the non-homologous end-joining (NHEJ) DNA repair process. DDRI-18 is an effective chemosensitizing agent[1].
Related Catalog
References

[1]. D W Jun, et al. Characterization of DDRI-18 (3,3'-(1H,3'H-5,5'-bibenzo[d]imidazole-2,2'-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response. Br J Pharmacol. 2012 Sep;167(1):141-50.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 835.8±75.0 °C at 760 mmHg
Molecular Formula C26H20N6
Molecular Weight 416.48
Flash Point 503.4±24.3 °C
Exact Mass 416.174957
LogP 4.08
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.804
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335-H413
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38
RIDADR NONH for all modes of transport

 Synonyms

Benzenamine, 3,3'-[6,6'-bi-1H-benzimidazole]-2,2'-diylbis-
3,3'-[6,6'-bi-1H-Benzimidazole]-2,2'-diylbis-benzenamine
MFCD01137750
3,3'-(1H,1'H-5,5'-Bibenzimidazole-2,2'-diyl)dianiline
DDRI-18