Isopedicin

Modify Date: 2024-01-09 18:20:52

Isopedicin Structure
Isopedicin structure
Common Name Isopedicin
CAS Number 4431-42-9 Molecular Weight 330.33
Density 1.3±0.1 g/cm3 Boiling Point 552.9±50.0 °C at 760 mmHg
Molecular Formula C18H18O6 Melting Point N/A
MSDS N/A Flash Point 202.8±23.6 °C

 Use of Isopedicin


Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity[1].

 Names

Name 2,4,6-Trimethylbenzamide
Synonym More Synonyms

 Isopedicin Biological Activity

Description Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity[1].
Related Catalog
References

[1]. Hwang TL, et al. Potent inhibition of superoxide anion production in activated human neutrophils by isopedicin, a bioactive component of the Chinese medicinal herb Fissistigma oldhamii. Free Radic Biol Med. 2009 Feb 15;46(4):520-8.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 552.9±50.0 °C at 760 mmHg
Molecular Formula C18H18O6
Molecular Weight 330.33
Flash Point 202.8±23.6 °C
Exact Mass 330.110352
PSA 74.22000
LogP 2.92
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.584

 Synonyms

6-Hydroxy-5,7,8-trimethoxy-2-phenyl-chroman-4-on
4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy-5,7,8-trimethoxy-2-phenyl-, (2S)-
6-Hydroxy-5,5-dimethyl-5,6-dihydro-benz<c>acridin
5,5-Dimethyl-6-hydroxy-5,6-dihydrobenz<c>acridin
6-hydroxy-5,7,8-trimethoxy-2-phenyl-chroman-4-one
(2S)-6-Hydroxy-5,7,8-trimethoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
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