2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one

Modify Date: 2023-02-04 16:34:23

2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one structure	Common Name	2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
	CAS Number	444020-71-7	Molecular Weight	408.15
	Density	2.6±0.1 g/cm3	Boiling Point	723.5±70.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₃IN₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	391.4±35.7 °C

Use of 2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one

2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Amino-5-iodo-7-(β-D-ribofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
Synonym	More Synonyms

Description	2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.6±0.1 g/cm3
Boiling Point	723.5±70.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₃IN₄O₅
Molecular Weight	408.15
Flash Point	391.4±35.7 °C
Exact Mass	407.993042
LogP	0.29
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.958

2-Amino-5-iodo-7-(β-D-ribofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro-5-iodo-7-β-D-ribofuranosyl-

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2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one

Use of 2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one

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