LEVOBUNOLOL

Modify Date: 2024-01-13 18:14:56

LEVOBUNOLOL Structure
LEVOBUNOLOL structure
Common Name LEVOBUNOLOL
CAS Number 47141-42-4 Molecular Weight 291.38500
Density N/A Boiling Point N/A
Molecular Formula C17H25NO3 Melting Point 205 - 210ºC
MSDS N/A Flash Point N/A

 Use of LEVOBUNOLOL


Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].

 Names

Name levobunolol
Synonym More Synonyms

 LEVOBUNOLOL Biological Activity

Description Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].
Related Catalog
Target

β-adrenoceptor

References

[1]. Mohammadi M, et al. Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery. Acta Biomater. 2018 Jun;73:90-102.

[2]. Kumar, N, et al. Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy. Futur J Pharm Sci 6, 109 (2020).

[3]. Zhang M, et al. Superior oblique myokymia treated with levobunolol. J AAPOS. 2018 Feb;22(1):67-69.e2.

 Chemical & Physical Properties

Melting Point 205 - 210ºC
Molecular Formula C17H25NO3
Molecular Weight 291.38500
Exact Mass 291.18300
PSA 58.56000
LogP 2.72430
Storage condition -20?C Freezer, Under Inert Atmosphere

 Safety Information

HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

LEVOBUNOLOL
Betagan
Levobunololum
MFCD00864586
Akbeta
5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one
UNII-G6317AOI7K