47141-42-4

47141-42-4 structure

Name: LEVOBUNOLOL
Chemical Name: levobunolol
CAS Number: 47141-42-4
Molecular Formula: C₁₇H₂₅NO₃
Molecular Weight: 291.38500
Catalog: API Circulatory system medication Antiarrhythmic drug
Create Date: 2018-07-01 12:48:10
Modify Date: 2024-01-13 18:14:56
Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].

Name	levobunolol
Synonyms	LEVOBUNOLOL Betagan Levobunololum MFCD00864586 Akbeta 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one UNII-G6317AOI7K

Description	Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	β-adrenoceptor
References	[1]. Mohammadi M, et al. Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery. Acta Biomater. 2018 Jun;73:90-102. [2]. Kumar, N, et al. Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy. Futur J Pharm Sci 6, 109 (2020). [3]. Zhang M, et al. Superior oblique myokymia treated with levobunolol. J AAPOS. 2018 Feb;22(1):67-69.e2.

Melting Point	205 - 210ºC
Molecular Formula	C₁₇H₂₅NO₃
Molecular Weight	291.38500
Exact Mass	291.18300
PSA	58.56000
LogP	2.72430
Storage condition	-20?C Freezer, Under Inert Atmosphere

HS Code	2922509090

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%