Fmoc-MMAE

Modify Date: 2024-01-03 14:24:03

Fmoc-MMAE structure	Common Name	Fmoc-MMAE
	CAS Number	474645-26-6	Molecular Weight	940.22
	Density	1.1±0.1 g/cm3	Boiling Point	1036.4±65.0 °C at 760 mmHg
	Molecular Formula	C₅₄H₇₇N₅O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	580.6±34.3 °C

Use of Fmoc-MMAE

Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC[1].

Name	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide
Synonym	More Synonyms

Description	Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	Auristatin
References	[1]. Pan D, et al. An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer. Cancer Med. 2020;9(24):9529-9540.

Density	1.1±0.1 g/cm3
Boiling Point	1036.4±65.0 °C at 760 mmHg
Molecular Formula	C₅₄H₇₇N₅O₉
Molecular Weight	940.22
Flash Point	580.6±34.3 °C
Exact Mass	939.572144
LogP	8.60
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.556

L-Valinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (9H-fluoren-9-yl)methyl((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Fmoc-MMAE
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

Fmoc-MMAE suppliers

Price: ￥880/50 mg

Reference only. check more Fmoc-MMAE price

Fmoc-MMAE

Use of Fmoc-MMAE

Names

Fmoc-MMAE Biological Activity

Chemical & Physical Properties

Synonyms