Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI)

Modify Date: 2024-01-24 18:06:09

Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI) Structure
Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI) structure
Common Name Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI)
CAS Number 4753-02-0 Molecular Weight 307.10
Density 1.9±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H11BrN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI)


2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-Bromo-2'-deoxy-D-uridine
Synonym More Synonyms

 Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI) Biological Activity

Description 2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Molecular Formula C9H11BrN2O5
Molecular Weight 307.10
Exact Mass 305.985138
PSA 104.55000
LogP -0.93
Index of Refraction 1.642

 Synonyms

21-Brom-21-desoxyuridin
2'-Bromo-2'-desoxyuridin
Uridine, 2'-bromo-2'-deoxy-
2'-Bromo-2'-deoxyuridine
2'-bromo-2'-deoxy-uridine
2'-Brom-2'-desoxy-uridin
1-Piperidino-2-brom-1-phenyl-aethan
2'-Brom-2'-deoxy-uridin
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