2-(4-Nitrophenyl)Quinazolin-4(1H)-One

Modify Date: 2024-01-02 07:25:59

2-(4-Nitrophenyl)Quinazolin-4(1H)-One structure	Common Name	2-(4-Nitrophenyl)Quinazolin-4(1H)-One
	CAS Number	4765-59-7	Molecular Weight	267.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₉N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(4-Nitrophenyl)Quinazolin-4(1H)-One

TNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM[1].

Name	2-(4-nitrophenyl)-1H-quinazolin-4-one
Synonym	More Synonyms

Description	TNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PARP Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
References	[1]. Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.

2-<4-Nitro-phenyl>-4-oxo-chinazolin

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