Lecanoricacid

Modify Date: 2024-01-05 16:48:55

Lecanoricacid structure	Common Name	Lecanoricacid
	CAS Number	480-56-8	Molecular Weight	318.278
	Density	1.5±0.1 g/cm3	Boiling Point	557.1±50.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₄O₇	Melting Point	175-176ºC
	MSDS	N/A	Flash Point	208.3±23.6 °C

Use of Lecanoricacid

Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1].

Name	o-orsellinate depside
Synonym	More Synonyms

Description	Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Umezawa H, et al. Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. J Antibiot (Tokyo). 1974;27(8):587-596.

Density	1.5±0.1 g/cm3
Boiling Point	557.1±50.0 °C at 760 mmHg
Melting Point	175-176ºC
Molecular Formula	C₁₆H₁₄O₇
Molecular Weight	318.278
Flash Point	208.3±23.6 °C
Exact Mass	318.073944
PSA	124.29000
LogP	4.39
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.675

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VH3709950

CHEMICAL NAME :: beta-Resorcylic acid, 6-methyl-, 4-(6-methyl-beta-resorcylate)

CAS REGISTRY NUMBER :: 480-56-8

BEILSTEIN REFERENCE NO. :: 2172778

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H14-O7

MOLECULAR WEIGHT :: 318.30

WISWESSER LINE NOTATION :: QVR BQ F1 DOVR DQ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,587,1974

Hazard Codes	Xi

Precursor 4
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DownStream 9
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CAS#:124-38-9 Carbon dioxide