Gyrophoric acid

Modify Date: 2024-01-05 19:37:15

Gyrophoric acid structure	Common Name	Gyrophoric acid
	CAS Number	548-89-0	Molecular Weight	468.410
	Density	1.5±0.1 g/cm3	Boiling Point	693.9±55.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₂₀O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	238.5±25.0 °C

Use of Gyrophoric acid

Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2].

Name	4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid
Synonym	More Synonyms

Description	Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Gyrophoric acid (200 μM) leads to significant decrease of mitochondrial membrane potential in ovarian cancer cells A2780 after 24 h long exposure but not in HT-29 colon adenocarcinoma cells. Gyrophoric acid significantly inhibits cell growth and affects the expression of Bcl-2, Bax and Hsp70 proteins but only on higher concentration in A375 melanoma cancer cells. Gyrophoric acid treatment on HeLa cells clearly indicates ROS production and apoptosis as form of occurred cell death. Moreover, DNA damage and changing activity of stress/survival proteins as p38MAPK, Erk1/2 and Akt mediated by Gyrophoric acid treatment confirm pro-apoptotic potential[2].
References	[1]. Kosanic M, et al. Biological activities and chemical composition of lichens from Serbia. EXCLI J. 2014;13:1226-1238. Published 2014 Nov 18. [2]. Goga M, et al. Oxidative stress mediated by gyrophoric acid from the lichen Umbilicaria hirsuta affected apoptosis and stress/survival pathways in HeLa cells. BMC Complement Altern Med. 2019;19(1):221. Published 2019 Aug 19.

Density	1.5±0.1 g/cm3
Boiling Point	693.9±55.0 °C at 760 mmHg
Molecular Formula	C₂₄H₂₀O₁₀
Molecular Weight	468.410
Flash Point	238.5±25.0 °C
Exact Mass	468.105652
PSA	170.82000
LogP	6.62
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.686

Hazard Codes	Xi

Precursor 0
DownStream 5
CAS#:480-64-8 o-Orsellinic acid CAS#:3187-58-4 Methyl 2,4-dihy... CAS#:480-56-8 Lecanoricacid CAS#:504-15-4 Orcinol
CAS#:38862-71-4 benzyl 2,4-dihy...

Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester

4-({4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl}oxy)-2-hydroxy-6-methylbenzoic acid

Gyrophoric acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Gyrophoric acid
Price: Click To Check
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BioBioPha
China
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Gyrophoric acid
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DC Chemicals Limited
China
Product Name: Gyrophoric acid
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: GYROPHORIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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