Isothipendyl

Modify Date: 2024-01-09 22:54:34

Isothipendyl Structure
Isothipendyl structure
 Common Name Isothipendyl
CAS Number 482-15-5 Molecular Weight 285.40700
Density 1.167g/cm3 Boiling Point 421.3ºC at 760mmHg
Molecular Formula C16H19N3S Melting Point N/A
MSDS N/A Flash Point 208.6ºC

 Use of Isothipendyl


Isothipendyl (AY 56012), an azaphenothiazine derivative, is a potent histamine 1 (H1) receptor antagonist. Isothipendyl is a primary metabolite[1].

 Names

Name N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine
Synonym More Synonyms

 Isothipendyl Biological Activity

Description Isothipendyl (AY 56012), an azaphenothiazine derivative, is a potent histamine 1 (H1) receptor antagonist. Isothipendyl is a primary metabolite[1].
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.167g/cm3
Boiling Point 421.3ºC at 760mmHg
Molecular Formula C16H19N3S
Molecular Weight 285.40700
Flash Point 208.6ºC
Exact Mass 285.13000
PSA 44.67000
LogP 3.69940
Vapour Pressure 2.63E-07mmHg at 25°C
Index of Refraction 1.62

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU8571000
CHEMICAL NAME :
10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(2-(dimethylamino)propyl)-
CAS REGISTRY NUMBER :
482-15-5
BEILSTEIN REFERENCE NO. :
0256817
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H19-N3-S
MOLECULAR WEIGHT :
285.44
WISWESSER LINE NOTATION :
T C666 BN DN ISJ B1Y1&N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
222 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,489,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
62 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,489,1958

 Synonyms

Actapront
Odantol
Nilergex
Isothipendylum
isothiopendyl
Isothipendyl
Udantol
Andanton
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Chemsrc provides Isothipendyl(CAS#:482-15-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Isothipendyl are included as well.>> amp version: Isothipendyl

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