5-Valine-angiotensin I
5-Valine-angiotensin I structure
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Common Name | 5-Valine-angiotensin I | ||
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| CAS Number | 484-43-5 | Molecular Weight | 1282.45000 | |
| Density | 1.44g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C61H87N17O14 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of 5-Valine-angiotensin I5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2]. |
| Name | asp-arg-val-tyr-val-his-pro-phe-his-leu |
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| Synonym | More Synonyms |
| Description | 5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2]. |
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| Related Catalog | |
| In Vitro | 5-Valine-angiotensin I shows myotropic effect (muscle contraction) on isolated rat colon after nonspecific desensitization of receptors with acetylcholine[2]. |
| Density | 1.44g/cm3 |
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| Molecular Formula | C61H87N17O14 |
| Molecular Weight | 1282.45000 |
| Exact Mass | 1281.66000 |
| PSA | 493.22000 |
| LogP | 3.44270 |
| Index of Refraction | 1.671 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Renal responses to AT1 receptor blockade.
Am. J. Hypertens. 13 , 45S-54S, (2000) Because of the importance of the renin-angiotensin system in the pathophysiology of hypertension and in mediating associated alterations in renal function, angiotensin II (Ang II) AT1 receptor blocker... |
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Purification and identification of endogenous anti-opioid substances from bovine brain.
Biochem. Biophys. Res. Commun. 126(1) , 587-93, (1985) Two fractions with high potency for reversing the inhibitory effect of Met-enkephalin on the electrically induced contractility of guinea-pig ileum have been purified from bovine brain extract. Unexpe... |
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Determination of renin activity in human plasma by column-switching high-performance liquid chromatography with fluorescence detection. Miyazaki T, Kai M, Ohkura Y.
J. Chromatogr. A. 490 , 43-51, (1989)
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| [Val5]-Angiotensin I bovine |
| Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu-OH |
| L-Asp-L-Arg-L-Val-L-Tyr-L-Val-L-His-L-Pro-L-Phe-L-His-L-Leu-OH |